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October 15, 2025Jurnal Teknologi LaboratoriumOpen Access

Indonesian medicinal plants as potential candidates for alpha-glucosidase inhibitor : A comprehensive literature review for anti-diabetic therapy

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Authors

JNJoanne NatalieMGMarisca Evalina GondokesumoMWMariana Wahjudi

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Overview

Literature review identifies 40 Indonesian plants with potential alpha-glucosidase inhibition, suggesting a new approach for diabetes treatment.

Key Points

  • The review identifies 40 Indonesian medicinal plants with potential alpha-glucosidase inhibitory effects, supporting their role in anti-diabetic therapy.
  • In vitro studies show that compounds like flavonoids and polyphenols effectively inhibit the alpha-glucosidase enzyme, potentially lowering blood glucose levels.
  • Most studies utilized spectrophotometric assays to measure alpha-glucosidase activity, indicating rigorous testing methods over the past decade.
  • Findings highlight the competitive inhibition mechanism, suggesting Indonesian plants could lead to safer, plant-based diabetes treatments.

Cite This Study

Natalie et al. (2025) studied this question.

synapsesocial.com/papers/68f01110f081da0584b5671bhttps://doi.org/10.29238/teknolabjournal.v14i2.478
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Anti-diabetic Potential of Medicinal Plants: A Review2026
  2. 2Alpha-amylase and Alpha-glucosidase Inhibitory Activities of Philippine Indigenous Medicinal Plants2024 · 1 citations
  3. 3Inhibition of Diabetes-Related Enzymes by Plant Secondary Metabolites: A Promising Therapeutic Strategy2026 · 2 citations
  4. 4Research Progresses of Plant Polysaccharides with α-Glucosidase Inhibition activities2024
  5. 5Comparative Evaluation of In-Vitro Antidiabetic Activity of Selected Herbal Extracts Using α-Amylase and α-Glucosidase Inhibition Assays2026