Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
October 15, 2025International Journal of Scientific Research

Study on the Significance of Braf V600e Mutations in Melanoma Patients at a Tertiary Cancer Care Centre in Southern India

View Full Paper
Ask AI
Bookmark
Share

Authors

SCSuresh Babu M. C.Kidwai Memorial Institute of OncologyRDR. S. DarshanKidwai Memorial Institute of OncologyGSGuruprasad C. ShenoyKidwai Memorial Institute of Oncology

Discussion

Loading...

Member takes

Overview

Prospective observational study highlights correlation between BRAF mutations and melanoma in patients, indicating advanced stages are more prevalent.

Key Points

  • BRAF V600E mutations were found in 14 of 54 melanoma patients, indicating a significant presence of this mutation.
  • Among patients studied, 31 presented with stage 4 disease, representing 57.4% of cases, demonstrating advanced disease prevalence.
  • The study revealed a significant correlation between higher Ki67 levels and BRAF mutation positivity in eight patients.
  • Melanoma cases are relatively rare in India, often presenting at advanced stages, emphasizing the need for targeted therapies.

Cite This Study

C et al. (2025) studied this question.

synapsesocial.com/papers/68f02c7d616531447b5f9367https://doi.org/10.36106/ijsr/9708606
View Full Paper
Ask AI
Bookmark
Share