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This is a Experimental Study study.

October 16, 2025Open Access

Green exfoliation of 2D nanomaterials using Cyrene as a solvent

PMPedro Bertino MoreiraUniversidade Nova de Lisboa JMJoão MendesAdministração Regional de Saúde de Lisboa e Vale do Tejo TCTomás CalmeiroUniversity of Lisbon

Key Points

Using Cyrene as a solvent increases the quality of 2D nanomaterials, reducing environmental impact.
Conventional solvents like dimethylformamide and N-methyl-2-pyrrolidone are toxic, posing risks to health.
Liquid-phase exfoliation (LPE) proves to be a scalable method for producing high-quality 2D materials with less toxicity.
Switching to green solvents can improve synthesis of 2D nanomaterials while maintaining product efficacy.

Abstract

Liquid-phase exfoliation (LPE) is a versatile and scalable method for producing high-quality two-dimensional materials (2DMs). However, commonly used solvents such as dimethylformamide (DMF) or N-methyl-2-pyrrolidone (NMP) are highly toxic, limiting...

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