Annulation reaction synthesizes spirocyclopropane derivatives using (E)-2-ylidene-3-cyclohexenones and sulfur ylides, indicating potential for versatile applications.
A diastereoselective [2 + 1] annulation reaction for synthesis of spirocyclopropane-fused 3-cyclohexenone derivatives has been established, utilizing easily preparable ( E )-2-ylidene-3-cyclohexenones and stabilized sulfur ylides.
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Li et al. (2025) studied this question.
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