A viscosity-activated and tumor-specific NIR probe for precise imaging of cancer cells

Q: What type of study is this?

This is a Experimental Study study.

Xue‐Ru Wu; Lingling Cao; Qiuyue Zhao; Junjie Kou; Yinghong Li; Fanpeng Kong; Bo Tang

doi:10.1039/d5cc04607f

January 1, 2025Chemical Communications

A viscosity-activated and tumor-specific NIR probe for precise imaging of cancer cells

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Key Points

The NIR fluorescent probe activates fluorescence in tumor cells, allowing for precise imaging.
DHX-Biotin-V selectively detects viscosity with minimal interference from pH or polarity.
Targeting biotin receptors enables the probe's entry into tumor cells for effective detection.
This approach may enable more accurate cancer imaging and monitoring treatments in affected tissues.

Implication

Novel NIR probe detects viscosity in tumor cells, suggesting enhanced imaging precision.

Abstract

We developed DHX-Biotin-V, an NIR fluorescent probe that selectively detects viscosity with minimal interference from polarity or pH. It targets biotin receptors to enter tumor cells, where its fluorescence activates...

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Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/68f0492fe559138a1a06e11f https://doi.org/10.1039/d5cc04607f

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A viscosity-activated and tumor-specific NIR probe for precise imaging of cancer cells

Key Points

Implication

Abstract

Discussion

Cite This Study

A viscosity-activated and tumor-specific NIR probe for precise imaging of cancer cells

Key Points

Implication

Abstract

Discussion

Cite This Study

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