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October 16, 2025Open Access

Doxycycline for Macrolide-Resistant Mycoplasma pneumoniae Pneumonia in Children: Analysis of Efficacy and Safety Across Different Age Groups

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Authors

JZJiawen ZhuXMXia MaoJMJiacheng Mo

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Overview

Retrospective cohort study examines doxycycline effectiveness and safety in pediatric pneumonia, highlighting treatment responses across age groups.

Key Points

  • Doxycycline significantly reduces hospitalization duration in older children compared to intravenous azithromycin.
  • In children younger than 8 years, switching from azithromycin to doxycycline improves recovery metrics and shortens hospital stay.
  • Safety results indicate mild adverse reactions to doxycycline, reinforcing its acceptable tolerance in pediatric patients.
  • Early switching to doxycycline in severe cases enhances treatment outcomes, suggesting it as a viable option for resistant pneumonia.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/68f04935e559138a1a06e275https://doi.org/10.20944/preprints202510.0832.v1
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