Laboratory investigation shows pumpkin seed oil's antibacterial activity against multidrug-resistant foodborne pathogens, suggesting potential as a natural alternative treatment.
This study aimed to investigate the antibacterial activity of cold-pressed pumpkin seed oil (Cucurbita maxima) against selected foodborne multidrug-resistant (MDR) pathogens. The oil's inhibitory effect was evaluated against Klebsiella pneumoina, Salmonella enterica, Bacillus cereus, and Staphylococcus aureus using the agar well diffusion method. Seven concentrations (5%-100%) were tested with amoxicillin as the positive control and dimethyl sulphoxide (DMSO) 5% as the negative control. The results demonstrated that pumpkin seed oil exhibited a concentration-dependent antibacterial activity. Significant inhibition was observed even at low concentrations (5%), with significant differences between the different concentrations (p<0.05). These findings suggest that Cucurbita maxima seed oil promises to be a natural antibacterial agent and could serve as an alternative for managing MDR foodborne infections.
No takes yet. Share an insight, caveat, or question.
Esra Elmaghbub (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: