Observational analysis identifies predictive factors for histological upstaging and downstaging in gastric lesions, suggesting improvements in diagnostic accuracy.
Background Endoscopic biopsies are insufficient for the correct diagnosis of gastric lesions since there has been described a discrepancy rate between endoscopy biopsies and endoscopic resection specimens of 25–32%. The aim of this study was to evaluate factors associated with upstaging and downstaging of biopsy results following gastric endoscopic submucosal dissection (ESD).
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Ferreira et al. (2025) studied this question.
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