Acute idiopathic blind spot enlargement syndrome mimicking optic neuropathy

Optic neuropathy may be mimicked by retinal diseases like acute idiopathic blind spot enlargement (AIBSE) syndrome. We describe a 43-year-old woman with unilateral loss of vision associated with optic disc pallor. Following the clinical examination, the patient was submitted to magnetic resonance imaging to rule out structural changes and optic nerve enhancement. Multimodal retinal imaging revealed a pigmentary change adjacent to the optic nerve. Finally, AIBSE was confirmed by automated visual field testing, establishing the diagnosis.