Oscillopsia unmasked: Anti-epileptic drug interaction at therapeutic doses

Anti-epileptic drugs (AEDs) are known to be associated with visual side effects, including oscillopsia and nystagmus. We report the case of a 22-year-old male with symptomatic focal seizures and organic affective disorder, on multiple AEDs, who developed disabling oscillopsia 2 weeks after the addition of valproate at therapeutic doses for seizure exacerbation. Valproate was discontinued, leading to complete resolution of symptoms within 5 days. This case highlights the role of AED interactions in causing reversible ocular motor toxicity.