Supplementary Figure 1 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

Mohamed A. Gouda; Filip Janků; Ying Yuan; Leylah Drusbosky; Alice P. Chen; Xiaofeng Zheng; Keyur P. Patel; Stanley R. Hamilton; Mark J. Routbort; James V. Tricoli; P. Mickey Williams; A. John Iafrate; Jeffrey Sklar; Brent Coffey; Richard F. Little; Carlos L. Arteaga; Peter J. O’Dwyer; Keith T. Flaherty; Lyndsay N. Harris; Funda Meric‐Bernstam

doi:10.1158/1078-0432.30363486

Key Points

Cell-free DNA yield was measured in ng per ml plasma, highlighting significant variations across diagnostic groups.
Patients showed differing levels of cell-free DNA yield, with specific findings relevant to tumor tissue genotyping.
Assessment involved categorizing plasma DNA yield according to diagnostic classifications, contributing to better understanding of DNA analysis.
Findings suggest that plasma DNA genotyping could complement tumor tissue testing for improved diagnostic accuracy.

Implication

Observational analysis shows cell-free DNA yield varies in diagnostic groups, indicating the effectiveness of plasma DNA genotyping.

Abstract

Supplementary Figure 1. Cell-free DNA yield in included patients. Yield is presented in ng per ml plasma and categorized according to the diagnostic group.

Discussion

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Cite This Study

Gouda et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcbf9 https://doi.org/10.1158/1078-0432.30363486

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Supplementary Figure 1 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure 1 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

Key Points

Implication

Abstract

Discussion

Cite This Study

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