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October 17, 2025TransfusionOpen Access

Patient characteristics and clinical determinants of outpatient red cell transfusions

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Authors

NHNora HemesathDFDaniel FürstMHMarijn J. Holl

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Overview

Retrospective analysis examines outpatient red blood cell transfusion determinants, indicating patient characteristics influence outcomes.

Key Points

  • Outpatient RBC transfusions are primarily indicated for blood disorders and solid tumors, accounting for 82% of usage.
  • On average, hemoglobin increased by 1.04 g/dL per unit transfused, with male sex and lower pretransfusion Hb as negative factors.
  • The analysis involved 804 patients over 5591 visits, revealing key correlations between patient height, sex, and transfusion frequency.
  • Nonsevere adverse reactions occurred in up to 0.24% of transfusions, emphasizing the need for careful monitoring.

Cite This Study

Hemesath et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcc33https://doi.org/10.1111/trf.18428
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Also Consider

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  1. 1Early Haemoglobin response after single‐unit red blood cell transfusion predicts repeat transfusion in hospitalised adults: A prospective cohort study and clinical prediction model2026
  2. 2Patterns and Predictors of Red Blood Cell Transfusion in the Pediatric Intensive Care Unit: A Retrospective Cohort Study2026
  3. 3Impact of red blood cell transfusion on clinical and hematological outcomes in hospitalized patients2026
  4. 4A Retrospective Analysis of Blood Component Utilization and Transfusion-Related Factors in a Diverse Patient Population2026
  5. 5Red blood cell ordering pattern following the introduction of a transfusion procedure based on haemoglobin concentration and anaemia symptoms: A retrospective study2025