Observational analysis reveals time to sustained myeloid recovery affected by clonal hematopoiesis and ferritin levels in patients undergoing CAR T-cell therapy.
Figure S4. (A) Time to sustained myeloid recovery stratified by CH-R alone, with medians and hazard ratio (HR) with 95% confidence interval (CI) shown. (B) Time to sustained myeloid recovery, stratified by low (<300 ng/mL) or high (≥300 ng/mL) baseline ferritin (ferr.) and by CH-R, with medians and adjusted hazard ratios (aHR) with 95% CI after multivariable model also including age, prior lines of therapy, and high-risk cytogenetic abnormalities. CH-R is clonal hematopoiesis restricted only to mutations in DNMT3A, TET2, ASXL1, or PPM1D.
No takes yet. Share an insight, caveat, or question.
Avigan et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: