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October 17, 2025Open Access

Screening for anxiety and depression: Validation of the PHQ-4 in a large sample of rehabilitation patients

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Authors

SGStefan GschwenterDepartment for Work and Pensions DGDominik GarberCentral European University BSBenedikt SteiningerUniversity of Vienna

Discussion

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Implication

This validation study assesses the PHQ-4's factorial and convergent validity in rehabilitation patients, indicating reliable screening for anxiety and depression.

Key Points

The PHQ-4 demonstrated an overall excellent fit for the two-factor solution for screening anxiety and depression.
Measurement invariance across age, gender, and most medical indications supports the PHQ-4's validity in diverse rehabilitation settings.
Reliability indices for the two-factor solution are adequate for a screening instrument, making it trustworthy for clinical use.
Ordinal logistic regression indicated significant associations with age and patient-reported outcomes, reinforcing the PHQ-4's convergent validity.

Cite This Study

Gschwenter et al. (2025) studied this question.

synapsesocial.com/papers/68f199ccde32064e504dd1f2 https://doi.org/10.1101/2025.10.13.25337934

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Implication

This validation study assesses the PHQ-4's factorial and convergent validity in rehabilitation patients, indicating reliable screening for anxiety and depression.

Screening for anxiety and depression: Validation of the PHQ-4 in a large sample of rehabilitation patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Screening for anxiety and depression: Validation of the PHQ-4 in a large sample of rehabilitation patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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