Case Study of Platelet Rich Plasma Treatment for Bilateral Long Head Biceps Femoris Tears in a Collegiate Football Player

Abstract Hamstring muscle injuries are common among athletes and often lead to prolonged recovery and time away from their competitive sports. Traditional conservative treatments might be insufficient or too aggressive in some severe cases, prompting interest in regenerative therapies such as platelet-rich plasma (PRP). PRP, especially when prepared in a way to exclude pro-inflammatory leukocytes, has shown potential to boost soft tissue healing.This case is about a collegiate football player with bilateral complete tears of the long head of the biceps femoris. PRP was initiated but due to early return to play, this athlete returned with a reinjury, more severe on the left side and associated with hematoma and early myositis ossificans. Over the course of five months, the athlete received nine PRP injections in total, along with one ultrasound-guided hydrodissection. Serial imaging showed progressive resolution of the hematoma, reduction of inflammation, and restoration of muscle integrity. Five months post-injury, the athlete made a full recovery with no reports of pain or functional limitations.This case shows the potential efficacy of PRP therapy in managing severe, recurrent hamstring injuries. When paired with appropriate imaging guidance and individualized rehabilitation, PRP can offer a non-surgical approach to complicated injuries and a full functional recovery.