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October 17, 2025JNCI Cancer SpectrumOpen Access

Racial and ethnic differences in treatment and survival for hepatocellular carcinoma patients undergoing systemic therapy

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Authors

KLKelsey S. Lau‐MinATAngela C. TramontanoFIFranklin Iheanacho

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Overview

Retrospective cohort analysis reveals survival differences in hepatocellular carcinoma patients treated with systemic therapies, indicating ethnic disparities in healthcare access.

Key Points

  • Asian and Hispanic patients demonstrated better overall survival compared to White patients undergoing systemic therapy.
  • Patients receiving novel systemic therapies showed improved survival rates, with Asian patients more likely to access these treatments.
  • Black and Hispanic patients had similar rates of treatment receipt, highlighting potential inequalities in healthcare access.
  • Racial differences in survival outcomes worsened over time, emphasizing the need for further research into these disparities.

Cite This Study

Lau‐Min et al. (2025) studied this question.

synapsesocial.com/papers/68f199ccde32064e504dd2e2https://doi.org/10.1093/jncics/pkaf100
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Racial disparities in hepatocellular carcinoma (HCC) treatment and survival: A SEER-Medicare analysis.2024
  2. 2Racial and ethnical disparities in treatment outcomes in patients with advanced HCC who received first-line immunotherapy.2026
  3. 3Investigating disparities in hepatocellular carcinoma and their effect on patterns of systemic care: An updated analysis.2026
  4. 4Changing treatment patterns for hepatocellular carcinoma: A SEER-Medicare study.2024
  5. 5Examining disparities in the receipt of curative treatment for hepatocellular cancer (HCC): A multicenter retrospective study from 2016-2023.2024