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October 17, 2025CureusOpen Access

Early and Long-Lasting Hematologic Recovery in a Young Adult With Severe Aplastic Anemia Treated With Romiplostim, Horse-Anti-Thymocyte Globulin (ATG), and Cyclosporine A: A Case Report

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Authors

EKEichi KakizakiTHTakehiro HigashiKAKenichi Akao

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Overview

A case report reveals hematologic improvement in a young adult with aplastic anemia, suggesting early treatment benefits.

Key Points

  • Hematologic recovery was notably observed within two weeks of treatment in the patient.
  • Complete response was achieved by week five, with hemoglobin and platelet counts improving significantly.
  • Combination therapy included horse anti-thymocyte globulin, cyclosporine A, and romiplostim for effective treatment.
  • The case highlights the importance of prompt immunosuppressive therapy in young patients with severe aplastic anemia.

Cite This Study

Kakizaki et al. (2025) studied this question.

synapsesocial.com/papers/68f19f1ade32064e504dda64https://doi.org/10.7759/cureus.94634
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1[A new era in the treatment of aplastic anemia].2025
  2. 2Progress in medical therapy in aplastic anemia: why it took so long?2024 · 8 citations
  3. 3Trilineage hematopoietic recovery with romiplostim in a child with down syndrome and aplastic anemia: A case report and review of literature2024
  4. 4Romiplostim in the management of severe aplastic anemia: a comprehensive clinical review2026
  5. 5Rapid early remission in a patient with severe aplastic anemia: a case report of hetrombopag, cyclosporine, and danazol combination therapy2025