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October 18, 2025Frontiers in Cell and Developmental BiologyOpen Access

Long non-coding RNAs: Key regulators of stemness in breast cancer

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Authors

OTOlivia Tellez‐JiménezAOAlejandro Ordaz-RamosMFMarco Antonio Fonseca-Montaño

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Overview

This review highlights molecular mechanisms involving long non-coding RNAs in breast cancer stem cells, indicating their role as potential therapeutic targets.

Key Points

  • Long non-coding rnas are crucial in regulating cancer stem cells, which contribute to treatment resistance and recurrence in breast cancer.
  • Breast cancer poses significant challenges, including the high mortality rate and complications from cancer stem cell populations.
  • Understanding lncRNA functions in breast cancer may lead to new therapeutic strategies or biomarkers for better treatment outcomes.
  • This review discusses the regulation mechanisms of lncRNAs in maintaining stemness in breast cancer stem cells.

Cite This Study

Tellez‐Jiménez et al. (2025) studied this question.

synapsesocial.com/papers/68f396388da44caaba02c71fhttps://doi.org/10.3389/fcell.2025.1571873
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