Physiological Effect of Hypothyroidism on Blood Pressure in Women

Background: Hypothyroidism is a chronic disease that occurs when thyroid gland doesn't produce enough thyroid hormones and without treatment HT may lead to serious health problems such as cardiovascular and metabolic diseases. Objective: The study aims to measure the level of some serum parameters that may associated with the occurrence of hypertension in HT women. Methodology: 90 serum samples, divide equally as patient and control were collected in a private laboratory based on the diagnosis of an internist, ELISA technique was used to record the levels of samples serum TSH, renin, aldosterone, cortisol, vasopressin, while TG, Total chole, LDL-C, HDL-C were measured by spectrophotometer for both patients and healthy samples. SPSS version 26 was used in the statistical analysis of results (p≤0.05). Results: Increase in the serum TSH, renin, vasopressin, TG, Total chole, LDL-C, HDL-C in HT patients compared with control group, a significant increase in the level of systolic presser and diastolic presser in patients. TSH level showed a significant variation between patients under the effect of BMI and history of the disease and significant correlation was recorded between blood presser with TSH, renin and vasopressin. Conclusion: The women with HT showed an abnormality in the level of some hormones that are associated with hypertension.