SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in GtoPdb v.2025.3

Q: What type of study is this?

This is a Literature Review study.

Yoshikatsu Kanai

doi:10.2218/gtopdb/f141/2025.3

September 10, 2025IUPHAR/BPS Guide to Pharmacology CITEOpen Access

SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in GtoPdb v.2025.3

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Key Points

The SLC3 and SLC7 transporter families form functional complexes essential for amino acid transport.
These transporters exhibit a disulphide-linked heavy and light chain subunit structure, enhancing their function.
Investigative analysis reviews transporter composition and implications for amino acid uptake in cells.
Understanding these transporters is crucial for potential therapeutic interventions in amino acid metabolic disorders.

Implication

Analysis identifies structural features of SLC3 and SLC7 transporters, suggesting roles in amino acid transport.

Abstract

The SLC3 and SLC7 families combine to generate functional transporters, where the subunit composition is a disulphide-linked combination of a heavy chain (SLC3 family) with a light chain (SLC7 family) [1].

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Cite This Study

Yoshikatsu Kanai (2025) studied this question.

synapsesocial.com/papers/68f3eb011cfc5ad53f2908b6 https://doi.org/10.2218/gtopdb/f141/2025.3

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SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in GtoPdb v.2025.3

Key Points

Implication

Abstract

Discussion

Cite This Study

SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in GtoPdb v.2025.3

Key Points

Implication

Abstract

Discussion

Cite This Study

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