Identification of bioactive compounds from Lippia multiflora leaves by 13 C NMR analysis

Abstract Medicinal plants are real sources of bioactive molecules. Lippia multiflora is a plant used for its multiple medicinal virtues used in many traditional and phytotherapeutic cultures. The objective of this study was to enhance the plant's leaves by identifying the molecular structures present in the dichloromethane fraction of the hydroalcoholic extract. This fraction was obtained by maceration of the dried leaf ground material in an ethanol/water mixture (70/30: v/v) followed by liquid-liquid fractionations. Twelve (12) known compounds of the genus Lippia were identified by carbon-13 Nuclear Magnetic Resonance (13C NMR) of the plant's leaves. Among these 12 compounds, seven (07) are linear alkanes, three (03) are triglycerides and the other two (02) are: a cycloalkane (methyl cyclohexane) and an alkene (non-1-ene). Almost all of the molecules obtained had not yet been identified in the leaves of Lippia multiflora.Lippia multiflora leaves contain novel bioactive compounds of pharmacological interest.