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October 19, 2025F1000ResearchOpen Access

AmpSeqR: an R package for amplicon deep sequencing data analysis

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AmpSeqR improves accuracy of amplicon sequencing data analysis, enhancing low frequency clone detection in mixed samples.
The package integrates several R packages and includes features like data pre-processing and visualization to streamline analysis.
Existing pipelines often struggle with distinguishing true sequences from errors; AmpSeqR aims to resolve these issues effectively.
AmpSeqR is openly accessible on GitHub, supporting both biological and medical applications in diverse fields such as brain mosaicism.

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New bioinformatics package provides tools for processing amplicon sequencing data, facilitating analysis in infectious diseases and cancer.

Han et al. (2025) studied this question.

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New bioinformatics package provides tools for processing amplicon sequencing data, facilitating analysis in infectious diseases and cancer.