This study demonstrates enhanced wound healing in rabbits using a self-powered transparent electronic skin, suggesting a novel synergistic therapy approach.
A flexible, self-powered, and transparent electronic skin (e-skin) is constructed by combining endogenous electric field modulation and infrared thermal stimulation to accelerate wound healing. The e-skin comprises (1) a transparent conductive layer for real-time wound monitoring, fabricated by thermal deposition of hexadecyltrimethylammonium bromide (CTAB)-functionalized carbon nanotubes (C-MWCNTs) with polydimethylsiloxane (PDMS); (2) a photothermal interface using Pd@Au nanoframes for infrared therapy; and (3) self-powered electric fields mimicking bioelectric signals. Antibacterial assays of the e-skin showed >160% bacterial suppression at the peak output of 0.25–0.59 V and 90–140% suppression at the baseline output of 0.05–0.12 V. In vitro tests demonstrated 90% E. coli elimination within 10 min. In vivo studies on rabbits revealed a 50% reduction in healing time (7 days) via synergistic photothermal-electrical therapy. This e-skin offers a promising approach to advanced wound care.
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Wang et al. (2025) studied this question.
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