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This is a Quantitative Study study (also classified as: Experimental Study).

Resistance of Spodoptera frugiperda (Lepidoptera: Noctuidae) to the diamides chlorantraniliprole and flubendiamide: resistance development, heritability, inheritance and implications for management

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Laboratory selection showed high resistance development in Spodoptera frugiperda, indicating management strategies are essential.

Resistance to chlorantraniliprole increased by 198.7-fold after selection, while flubendiamide resistance grew by 136.5-fold.
The inheritance of resistance is autosomal, polygenic, and incompletely dominant, with heritability estimates at 0.15 for chlorantraniliprole and 0.16 for flubendiamide.
Laboratory bioassays showed moderate resistance levels to chlorantraniliprole and flubendiamide in a wild population compared to a susceptible lab population.
Management strategies should include insecticide rotation to counteract the developing resistance in Spodoptera frugiperda.

Salamat et al. (2025) studied this question.

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