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October 20, 2025Open Access

Systematic and Bibliometric Insights of Over Seven Decades of Sickle Cell Disease Research in Africa

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Authors

EJEmohchonne Utos JonathanKwararafa UniversityWDWadzani Palnam DaudaFederal University of AgriculturePAPeter AbrahamAhmadu Bello University

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Implication

Systematic literature review and bibliometric analysis reveal research trends and collaboration patterns in sickle cell disease.

Key Points

  • The study identifies over 2,100 articles on sickle cell disease research, revealing significant trends in Africa's public health landscape.
  • During the 74-year review, 7,178 authors contributed, with 167 articles published in 2022 marking the highest output year.
  • This systematic literature review and bibliometric analysis highlight evolving research from clinical understandings to therapeutic innovations.
  • Critical gaps remain in environments facilitating multi omics integration and participation in regional trials for effective sickle cell disease management.

Cite This Study

Jonathan et al. (2025) studied this question.

synapsesocial.com/papers/68f5a78aab63786de5b45ff5https://doi.org/10.1101/2025.10.14.25338027
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sickle Cell Disease in Africa: SickleInAfrica Registry in Ghana, Nigeria and Tanzania2025 · 10 citations
  2. 2Burden of sickle cell anemia in Africa: A systematic review and meta-analysis2025 · 6 citations
  3. 3Sickle Cell Disease in African Newspapers: A Content Analysis of News Coverage of Burden, Genetic Counselling and Newborn Screening, 2006‐20232026 · 1 citations
  4. 4The Sickle Africa Data Coordinating Centre (SADaCC): a data science hub for interdisciplinary sickle cell disease research and training2026
  5. 5Mapping the Scientific Landscape of Neuropathic Pain in Sickle Cell Disease: A Two‐Decade Bibliometric Perspective on an Underexplored Challenge2026