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October 21, 2025Frontiers in MedicineOpen Access

Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021

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Authors

TWTeng WangPeking UniversityLWLi WangNanjing University of Chinese MedicineXSXu SangJiangsu University

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Implication

Retrospective analysis reveals high morbidity and mortality from infectious diarrhea in children, highlighting unsafe water as a key risk factor.

Key Points

  • In 2021, there were approximately 168.73 million cases of infectious diarrhea among children under 14 globally.
  • The highest incidence of diarrhea was in neonates, with a notable 36.5% increase in the 10–14 age group since 1990.
  • Unsafe water sources were identified as the primary risk factor contributing to diarrheal deaths across all age groups.
  • Rotavirus was the leading pathogen causing mortality and disability-adjusted life years (DALYs) in children, with significant threats from unsafe sanitation.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68f74e597f21f73e19e5b377https://doi.org/10.3389/fmed.2025.1676249
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