This review addresses critical illness management through renin–angiotensin system modulation, highlighting therapeutic interventions and implications for intensivists.
In Brief The renin–angiotensin system plays a central role in the pathophysiology of critical illness, providing opportunities for therapeutic interventions such as angiotensin II in vasodilatory shock, alongside emerging possibilities for alternative renin–angiotensin system modulation.
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Calabrese et al. (2025) studied this question.
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