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Pharmacologists reveal novel oxygen-producing therapies, emphasizing the role of catalase in oxygen generation.
It is reported that pharmacologists in St. Petersburg and Izhevsk have discovered several new groups of medicines. Oxygen-producing antihypoxants, oxygen fuzes, and oxygen generator, invented on the initiative of Alexander Urakov, are listed in chronological order. It is shown that new drugs were created by physico-chemical repurposing of hydrogen peroxide from acidic antiseptics to warm alkaline hydrogen peroxide solution. The list of invented medicines, the composition of the ingredients of the created medicines and the mechanism of their action when applied topically are given. It is reported that the pharmacological target of oxygen-producing antihypoxants and oxygen fuze is the enzyme catalase, which is present in all tissues of the human body. It is indicated that catalase breaks down hydrogen peroxide into water and molecular oxygen at a tremendous rate. A chemical calculation is given showing that at a temperature of +42 °C, 1 liter of oxygen gas is formed from 100 ml of a 3% solution of hydrogen peroxide under the action of catalase. It is shown that the involvement of Professor Petr Shabanov in the study accelerated and expanded the development of oxygen-producing antihypoxants and led to the discovery of intrapulmonary, endobronchial and endotracheal injections, as well as a new group of drugs - oxygen generators. This information proves that Russia became the first country in the world to invent warm alkaline hydrogen peroxide solutions for inhalation, intrapulmonary, endotracheal and endobronchial injections for the purpose of emergency oxygenation of blood through the lungs in respiratory obstruction and asphyxia. In addition, Russia is also the birthplace of "oxygen fuzes" and the first individual portable oxygen generator for first aid in case of suffocation caused by lack of oxygen in the inhaled air.
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Urakova et al. (2025) studied this question.
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