Contribution of the Rostov physiological school to the development ofl.P. Pavlov’s idea of sleep physiology

To the 120tb anniversary of the Nobel Prize awarding to Academician I.P. Pavlov, the contribution of the Rostov physiological school to his ideas on sleep as a central problem of higher nervous activity is analyzed. Having become a professor at the Imperial University of Warsaw, I.P. Pavlov continued to supervise the work of the dissertation authors he was advising after the evacuation of the university during World War I to Rostov-on-Don. One of his students, N.A. Rozhansky, held the position of professor and head of the Department ofPhysiology at the Rostov Medical Institute and continued his work on the problem of sleep. Thanks to him, a whole generation of physiologists was raised, including Professor A.B. Kogan, who organized and headed the Research Institute of Neurocybemetic at Rostov State University, where, together with G.L. Feldman, he combined the work of neurophysiologists with the efforts of mathematicians as well as biophysicists to study and model sleep. The combination of the analysis of reorganization of neuronal ensembles in the sleep-wake cycle with lifetime brain biopsy in the dynamics of sleep and subsequent electron microscopy of slices allowed A.B. Kogan to reach a new level of understanding of I.P. Pavlov’s assertion about the sum of stimuli of wakefulness, conditioning the sum of exhaustion, which by humoral means automatically causes the inhibitory state of sleep.