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This is a Experimental Study study.

October 23, 2025Exploration of Targeted Anti-tumor TherapyOpen Access

Synergistic anticancer efficacy of optimized curcumin-piperine loaded magnetic nanoparticles for the treatment of colorectal cancer

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Authors

RPRitika PuriChandigarh University VAVimal AroraChandigarh University

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Implication

In vitro analysis shows that optimized curcumin-piperine magnetic nanoparticles reduce cell viability in colorectal cancer, suggesting improved drug delivery.

Key Points

Optimized curcumin-piperine magnetic nanoparticles reduced cell viability in colorectal cancer cells.
The IC50 of the nanoparticles indicates strong cytotoxicity with a particle size averaging 158.7 nm.
Assessment using cytotoxicity assays and confocal microscopy revealed a synergistic effect in HCT-116 cells.
These findings highlight the potential of targeted drug delivery using phytoconstituents for cancer therapy.

Cite This Study

Puri et al. (2025) studied this question.

synapsesocial.com/papers/68f9a0eb8ea8f2f37ee94ccb https://doi.org/10.37349/etat.2025.1002340

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Implication

In vitro analysis shows that optimized curcumin-piperine magnetic nanoparticles reduce cell viability in colorectal cancer, suggesting improved drug delivery.

Synergistic anticancer efficacy of optimized curcumin-piperine loaded magnetic nanoparticles for the treatment of colorectal cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

Synergistic anticancer efficacy of optimized curcumin-piperine loaded magnetic nanoparticles for the treatment of colorectal cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

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