What type of study is this?

This is a Quantitative Study study.

October 23, 2025Open Access

Structural connectome architecture and biological vulnerability shape cortical atrophy in cocaine use disorder

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Authors

ZHZiteng HanBeijing Institute of Technology TLTiantian LiuBeijing Institute of Technology KWKexin WangHarbin University of Science and Technology

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Implication

Analysis demonstrates white matter structure and functional connectivity affect cortical atrophy in cocaine use disorder, suggesting new therapeutic targets.

Key Points

Cortical atrophy is constrained by the white matter structural connectome.
Significant interactions identified between synaptic function and functional connectivity in cocaine use disorder.
Observational analysis utilizing transcranial magnetic stimulation assessed craving-responses and cortical atrophy in the brain.
Findings imply the urgent need for targeted interventions addressing neural homeostasis in cocaine use disorder.

Cite This Study

Han et al. (2025) studied this question.

synapsesocial.com/papers/68f9bad6d7353cfcfc68f32a https://doi.org/10.21203/rs.3.rs-7656463/v1

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Implication

Analysis demonstrates white matter structure and functional connectivity affect cortical atrophy in cocaine use disorder, suggesting new therapeutic targets.

Structural connectome architecture and biological vulnerability shape cortical atrophy in cocaine use disorder

Discussion

Member takes

Implication

Key Points

Cite This Study

Structural connectome architecture and biological vulnerability shape cortical atrophy in cocaine use disorder

Discussion

Member takes

Implication

Key Points

Cite This Study

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