Case report uncovers endoscopically discovered lesions resembling sessile polyps in asymptomatic patients, indicating potential GERD connection.
Ectopic sebaceous glands (ESGs) of the esophagus are very rare lesions, typically discovered incidentally during endoscopic examinations [1] [2]. In 1978, Ramakrishnan and Brinker reported the first case of esophageal ESGs identified via endoscopy [3]. Esophageal ESGs were found in 0.05% of asymptomatic subjects in a study involving a population undergoing gastric cancer screening [2]. Most reported patients with esophageal ESGs were either asymptomatic or presented with symptoms of gastroesophageal reflux disease (GERD [1] [2] [4]). Endoscopically, esophageal ESGs may appear as yellowish patches, plaques, or elevated lesions of varying sizes [1] [2] [4]. Although esophageal ESGs can be found throughout the esophagus, they were most commonly located in the middle and lower thirds [2] [4]. We report here a new case of esophageal ESGs that presented as multiple sessile polyps, with the diagnosis confirmed by histopathological examination.
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Liu et al. (2025) studied this question.
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