Clinical and laboratory predictors of mortality in Staphylococcus aureus bacteremia in a high-risk setting: a single-center retrospective analysis of Pitt score, SOFA, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio

Objective Staphylococcus aureus bacteremia (SAB) is associated with significant morbidity and mortality despite advancements in antimicrobial therapies. Timely risk stratification is critical to optimize patient outcomes. This study aimed to evaluate the prognostic value of clinical (Pitt bacteremia score [PBS]), combined clinical and laboratory (Sequential Organ Failure Assessment [SOFA]), and laboratory-based parameters (neutrophil-to-lymphocyte ratio [NLR] and platelet-to-lymphocyte ratio [PLR]) in patients with SAB.