Survival Outcomes With LUCAS-Assisted vs Manual CPR in In-Hospital Cardiac Arrest Obese Patients

Background : To compare 24-hour and 60-day survival after in-hospital cardiac arrest in overweight (BMI ≥ 25 kg/m²) and obese patients (BMI ≥ 30 kg/m²) resuscitated with LUCAS® assisted versus manual CPR, and to determine whether BMI modifies this association. Methods: Multicenter retrospective cohort of adult IHCA events at seven Mayo Clinic hospitals from January 2019 to January 2025. Cardiac arrests 0.14), indicating consistent effects across the BMI spectrum. Conclusion: In overweight and obese IHCA patients, LUCAS®-assisted mechanical CPR did not improve 24-hour or 60-day mortality versus high quality manual compressions, and effectiveness was independent of BMI.