Testicular Cancer–Associated Paraneoplastic Neurologic Syndromes

Ehab Harahsheh; M Bakri Hammami; Pranjal Gupta; Brian A. Costello; Bradley C. Leibovich; John C. Cheville; Αναστασία Ζεκερίδου; Charles L. Howe; Sean J. Pittock; Divyanshu Dubey

doi:10.1001/jamanetworkopen.2025.38584

October 21, 2025JAMA Network OpenOpen Access

Testicular Cancer–Associated Paraneoplastic Neurologic Syndromes

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Key Points

Testicular cancer is associated with paraneoplastic neurologic syndromes in adult males, revealing critical connections.
Neurological and serological profiles were evaluated in patients with testicular germ cell tumors.
Cohort study assessed the oncological characteristics of male patients with neurologic syndromes.
Findings highlight possible underlying mechanisms linking testicular cancer and neurologic manifestations.

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Implication

Cohort study reveals associations between testicular cancer and paraneoplastic neurologic syndromes in males, indicating further investigation is needed.

Abstract

This cohort study examines the oncological, neurological, and serological profiles of adult male patients with testicular germ cell tumors and paraneoplastic neurologic syndromes.

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Cite This Study

Harahsheh et al. (2025) studied this question.

synapsesocial.com/papers/68f9f86eb2c35e10cc4e3b45 https://doi.org/10.1001/jamanetworkopen.2025.38584

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Testicular Cancer–Associated Paraneoplastic Neurologic Syndromes

Key Points

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Implication

Abstract

Discussion

Cite This Study

Testicular Cancer–Associated Paraneoplastic Neurologic Syndromes

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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