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October 23, 2025BiomedicinesOpen Access

Impact of Early Initiation of Renal Replacement Therapy on Renal Recovery and Mortality in Critically Ill Patients with Acute Kidney Injury: A Prospective Cohort Study

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Authors

RMRayane Alves MoreiraSBSheila de Melo BorgesSBS Borges

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Overview

Prospective cohort study shows early renal replacement therapy may enhance renal recovery in critically ill patients, indicating timing impacts outcomes.

Key Points

  • Early renal replacement therapy improved recovery within 3 days but did not affect mortality rates.
  • Mortality analysis revealed no significant differences across groups at 20, 30, and 76 days post-treatment.
  • Observed clinical severity was higher in the early intervention group, emphasizing urgency in treatment choice.
  • Findings suggest that while early therapy boosts renal recovery, it does not lower the risk of mortality in acute kidney injury.

Cite This Study

Moreira et al. (2025) studied this question.

synapsesocial.com/papers/68fa1210f9f8b44535bfceachttps://doi.org/10.3390/biomedicines13112575
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