Analysis reveals a potential link between elevated carboxyhemoglobin and brain injury in very preterm infants, suggesting a role for oxidative stress.
Introduction Oxidative stress is one of the most important factors in the pathogenesis of neonatal brain injury in preterm infants. High level of carboxyhemoglobin (COHb) has been found to be associated with an increased risk for oxidative stress-related prematurity complications. Our aim was to assess the possible association between COHb fraction and brain growth and injury in very preterm infants (VPI).
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Remaschi et al. (2025) studied this question.
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