Frequency of Mutant Variants of Mycobacterium Tuberculosis Strains in the Regions of Azerbaijan and the Role of Mutation Types in the Effectiveness of Treatment

Currently, the fastest way to determine resistance to antituberculotic drugs (ATD) is the method of analyzing mutations associated with drug resistance. However, as studies show, the frequency of mutations involved in the formation of resistance may vary in different regions. For the effective use of molecular biological methods for diagnosing drug resistance, it is necessary to know the frequency of mutations associated with drug resistance in a particular region at a given time. Given the impact of mutational variants on the effectiveness of treatment, the correct selection of chemotherapy in the subsequent treatment of patients with tuberculosis can be considered conceptual. Correction of chemotherapy at an early stage of the disease is more appropriate from a pharmacoeconomic point of view since it is characterized by low cost and comparable effectiveness.