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October 31, 2025Open Access

Advances in Cytotoxicity Testing: From In Vitro Assays to In Silico Models

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Cytotoxicity testing has evolved to include advanced models like organ-on-chip technologies, increasing relevance.
Recent methods such as machine learning and QSAR offer improved predictive insights for assessing chemical toxicity.
Utilization of induced pluripotent stem cells provides ethical alternatives for studying organ-specific toxicity.
New approaches highlight the shift towards integrated, predictive frameworks in toxicological assessments.

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Advances in cytotoxicity testing reveal organ-on-chip technologies and machine learning may enhance predictive accuracy in toxicology.

Barbara Ziemba (2025) studied this question.

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