October 31, 2025Open Access

Arteriovenous Malformations (AVMs): Molecular Pathogenesis, Clinical Features, and Emerging Therapeutic Strategies

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Authors

NLNga LeUniversity of Miami YLY. LiHong Kong Polytechnic University GWGianni WalkerUniversity of Miami

Discussion

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Implication

Observational analysis shows AVMs arise from genetic, hemodynamic stress, and inflammation, indicating precision medicine may enhance therapeutic strategies.

Key Points

AVMs may be prevented and managed through precision medicine and multimodal imaging techniques.
Key factors in AVM pathogenesis include genetic mutations and abnormal signaling pathways relating to Notch and TGF-β/BMP.
Integrated genomic-imaging risk scores guide diagnosis and individualized management of AVMs.
Emerging devices and techniques like detachable-tip microcatheters improve treatment options for targeted AVM interventions.

Cite This Study

Le et al. (2025) studied this question.

synapsesocial.com/papers/6903fee5b25c631a4265fed6 https://doi.org/10.20944/preprints202510.2300.v1

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Implication

Observational analysis shows AVMs arise from genetic, hemodynamic stress, and inflammation, indicating precision medicine may enhance therapeutic strategies.

Arteriovenous Malformations (AVMs): Molecular Pathogenesis, Clinical Features, and Emerging Therapeutic Strategies

Discussion

Member takes

Implication

Key Points

Cite This Study

Arteriovenous Malformations (AVMs): Molecular Pathogenesis, Clinical Features, and Emerging Therapeutic Strategies

Discussion

Member takes

Implication

Key Points

Cite This Study

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