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Biopython 1.86 has been released and is available from our website and PyPI. This contains about nine months worth of updates, and is our first release with Python 3.14 support. See change-log in the news file (most of the changes are in Bio.Align and Bio.PDB). There have also been a few deprecations and removals of older code.
A 2025 study studied this question.
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