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November 1, 2025Open Access

Stimulus-specific recruitment of human amygdala neurons predicts episodic memory encoding success

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Authors

JXJiayang XiaoJDJonathan DaumeYSYousef Salimpour

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Overview

Single-neuron activity reveals memory formation in the amygdala, indicating potential targets for memory disorder interventions.

Key Points

  • Memory formation relies on specific local field potentials in the amygdala, enhancing encoding success.
  • Memory formation showed increased coherence between amygdala activity and hippocampal potentials in specific conditions.
  • The analysis involved single-neuron activity and local field potentials during recognition memory tasks.
  • Enhancing understanding of amygdala function may provide targets for addressing memory disorders.

Cite This Study

Xiao et al. (2025) studied this question.

synapsesocial.com/papers/69054ffa1a99e50463de67e9https://doi.org/10.1101/2025.10.29.685162
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human hippocampal reactivation of amygdala encoding-related gamma patterns during aversive memory retrieval2025
  2. 2Contributions of repeated learning to memory in humans: insights from single-neuron recordings in the hippocampus and amygdala2024 · 1 citations
  3. 3Neural Correlates of Emotional Memory Enhancement: The Role of Valence and Arousal2026 · 1 citations
  4. 4Heterogeneous plasticity of amygdala interneurons in associative learning and extinction2024
  5. 5A neuronal code for object representation and memory in the human amygdala and hippocampus2024