Prediction of osteoporosis at the sacrum using opportunistic CT of the abdomen and pelvis: a retrospective feasibility study in 277 patients comparing CT and QCT data

Xiao Yan; Wen Li; Wei Zhou; Miao Wei; Bangyuan Long; Jeffrey J. Pu; Fajin Lv

doi:10.21203/rs.3.rs-7716661/v1

October 31, 2025Open Access

Prediction of osteoporosis at the sacrum using opportunistic CT of the abdomen and pelvis: a retrospective feasibility study in 277 patients comparing CT and QCT data

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Key Points

Osteoporosis prediction based on sacral spine HU values showed high correlation with bone mineral density.
Receiver operating characteristic analysis indicated strong predictive efficacy with AUC values from 0.909 to 0.977 for individual vertebrae.
The predictive model incorporating sex, age, and vertebral HU values achieved an AUC of 0.981 for osteoporosis diagnosis.
Findings demonstrate the potential of opportunistic CT to improve osteoporosis screening and diagnosis accuracy.

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Implication

Retrospective analysis reveals strong correlation between sacral spine HU values and bone mineral density, suggesting improved osteoporosis prediction accuracy.

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Cite This Study

Yan et al. (2025) studied this question.

synapsesocial.com/papers/69054ffa1a99e50463de6999 https://doi.org/10.21203/rs.3.rs-7716661/v1

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Prediction of osteoporosis at the sacrum using opportunistic CT of the abdomen and pelvis: a retrospective feasibility study in 277 patients comparing CT and QCT data

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Prediction of osteoporosis at the sacrum using opportunistic CT of the abdomen and pelvis: a retrospective feasibility study in 277 patients comparing CT and QCT data

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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