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November 4, 2025Combinatorial Chemistry & High Throughput Screening

LINC00888 Promotes Gastric Cancer Growth and Metastasis by Sponging miR-145-5p to Regulate FZD7 Expression

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Authors

XZXuemei ZhouAZA.H. ZhangSMSuo Mo

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Overview

Analysis shows LINC00888 promotes cancer progression in gastric cancer, suggesting it as a potential therapeutic target and prognostic biomarker.

Key Points

  • LINC00888 promotes gastric cancer progression, influencing the miR-145-5p/FZD7 axis.
  • Upregulation of LINC00888 correlates with advanced stage and recurrence in gastric cancer patients.
  • Bioinformatics analyses and experimental validation employed to assess molecular functions involving LINC00888.
  • Integrating LINC00888 as a biomarker may enhance personalized management in gastric cancer treatment.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/690945348f2297dc13532ff2https://doi.org/10.2174/0113862073431030251019092839
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Also Consider

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  1. 1LncRNA LINC01579/miR-579-3p axis promotes gastric cancer progression via NOTCH1 pathway2026
  2. 2Knockdown of LINC00467 inhibits gastric cancer progression by modulating the sequestration of miR‑141‑3p2025
  3. 3Knockdown of LINC00467 inhibits gastric cancer progression by modulating the sequestration of miR-141-3p2024 · 1 citations
  4. 4LINC01711 facilitated gastric carcinoma progression by sponging miR-140-3p2025
  5. 5Exosomal LINC00853 promotes progression of gastric cancer via the MAP17/PDZK1/AKT signaling pathway2024 · 4 citations