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November 8, 2025Journal of Pharmacy & Pharmacognosy Research

GC-MS profiling and in silico multi-target docking of carvone, p-cymene, and linalool from Cuminum cyminum seeds extract against breast cancer proteins

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Authors

NANa’ilah Insani AlifiyahWNWirdatun NafisahRRRizki Rizki

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Overview

This analysis reveals anticancer activity of Cuminum cyminum compounds in breast cancer, suggesting pathways involving MDM2 and HER2.

Key Points

  • Selected compounds showed potential anticancer activity in breast cancer, indicating regulatory roles in apoptosis.
  • Predicted interactions between carcinogenic proteins and compounds like carvone and p-cymene demonstrate promising binding affinities against MDM2 and HER2.
  • Molecular docking studies using AutoDock Vina provide insights into the binding interactions of bioactive compounds from Cuminum cyminum extract.
  • Further experimental validation is necessary to confirm the anticancer efficacy of these compounds in vitro and in vivo.

Cite This Study

Alifiyah et al. (2025) studied this question.

synapsesocial.com/papers/690e8b75a5b062d7a4e738cahttps://doi.org/10.56499/jppres_14.1.2394
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Also Consider

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