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November 9, 2025Open Access

Taming polymorphism of tubule self-assembly using templated growth

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Authors

SLSirui LiuTVThomas E. VidebækWRW. Benjamin Rogers

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Overview

Analysis demonstrates improved assembly selectivity in cylindrical tubules with templated growth, indicating potential for reduced polymorphism.

Key Points

  • Tubules grow from defined seeds, decreasing polymorphism during self-assembly.
  • Efforts revealed a significant reduction in off-target assemblies, enhancing geometric accuracy.
  • Assessment used a combination of templated growth and multicomponent assembly strategies.
  • Research highlights economic and controllable methods for achieving monodisperse tubules in DNA-origami.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/690fdcdaf60c54d04ea38061https://doi.org/10.48550/arxiv.2511.02975
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