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November 9, 2025International Journal For Multidisciplinary ResearchOpen Access

Formulation and Evaluation of a Transdermal Patch of Diclofenac Sodium for Sustained Pain Relief

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Authors

HPH. Padmalatha

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Overview

Formulation shows sustained transdermal delivery of Diclofenac sodium for migraine, suggesting improved compliance with patches.

Key Points

  • Sustained transdermal delivery achieved with Diclofenac sodium patches, notably benefiting migraine management.
  • High dose showed drug release of 6.08 mg/cm2 /12 hrs with significant stability over 2 months.
  • Matrix type transdermal patches utilized polymers like HPMC K 15M and DBP as plasticizer in formulation.
  • Supports effective control of migraine, overcoming issues like first-pass metabolism in oral delivery.

Cite This Study

H. Padmalatha (2025) studied this question.

synapsesocial.com/papers/690fdce2f60c54d04ea383e2https://doi.org/10.36948/ijfmr.2025.v07i06.59960
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