Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
November 21, 2025Frontiers in Cellular and Infection MicrobiologyOpen Access

Bone and joint tuberculosis: clinical manifestation, diagnostic techniques and drug resistance analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

YYYingying YuanPLPengxiang LiXQXiangjie Qiu

Discussion

Loading...

Member takes

Overview

Retrospective study reveals high drug resistance in bone and joint tuberculosis patients, suggesting urgent attention for MDR and XDR TB.

Key Points

  • The study examines the characteristics and diagnostic challenges of bone and joint tuberculosis (BJTB) in Central China.
  • Retrospective analysis of patient data from Henan Provincial Chest Hospital between 2016 and 2022
  • Assessment of clinical manifestations, diagnostic techniques, and drug resistance patterns
  • 518 male and 384 female patients analyzed, with common symptoms including local pain and fever
  • GeneXpert MTB/RIF showed 91.6% sensitivity and 90.1% specificity for BJTB diagnosis
  • MDR-TB prevalence was 8.3% while XDR-TB was found in 1.6% of cases
  • Streptomycin and rifabutin were the most common drug resistance patterns

Cite This Study

Yuan et al. (2025) studied this question.

synapsesocial.com/papers/6924e3e6c0ce034ddc34eac9https://doi.org/10.3389/fcimb.2025.1687906
View Full Paper
Ask AI
Bookmark
Share