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November 21, 2025Annual Review of Medicine

Therapeutic Considerations in Preventing Chronic Kidney Disease

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Authors

SNSusanne B NicholasNNNiloofar NobakhtRARadica Z. Alicic

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Overview

This analysis shows the role of screening and new therapies in reducing cardiovascular disease risk in chronic kidney disease.

Key Points

  • The aim is to evaluate strategies for preventing chronic kidney disease and its complications.
  • Reviewed the impact of screening for at-risk individuals for chronic kidney disease.
  • Discussed therapeutic approaches including new guideline-directed medical therapies.
  • Analyzed the interplay of metabolic disorders like diabetes and obesity in chronic kidney disease progression.
  • Screening is essential as many patients are unaware of their chronic kidney disease diagnosis.
  • New therapies may reduce the risk of cardiovascular disease, the leading cause of death in CKD patients.
  • A multidisciplinary care approach enhances management and outcomes in chronic kidney disease.

Cite This Study

Nicholas et al. (2025) studied this question.

synapsesocial.com/papers/6924e3e6c0ce034ddc34eb01https://doi.org/10.1146/annurev-med-043024-013325
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Also Consider

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  1. 1Detecting and managing the patient with chronic kidney disease in primary care: A review of the latest guidelines2024 · 15 citations
  2. 2Chronic Kidney Disease2025 · 23 citations
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  4. 4Chronic kidney disease detection, staging and treatment in cardiovascular disease prevention2021 · 34 citations
  5. 5What every clinician needs to know about chronic kidney disease: Detection, classification and epidemiology2024 · 28 citations