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November 21, 2025Nutrition and DiabetesOpen Access

Bedtime snacking and glycemic deterioration in young children with Type 1 diabetes on multiple daily injections: a randomized controlled crossover trial

Tuğba Gökçe Kağan Ege Karakuş Gül Yeşiltepe Mutlu Serra Muradoğlu Elif Eviz Ecem Can Carmel Smart Şükrü Hatun Hülya Gökmen Özel

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Key Points

To evaluate the impact of bedtime snacking on glycemic control in young children with Type 1 diabetes.
Randomized controlled crossover design
Involved young children with Type 1 diabetes
Compared effects of bedtime snacking versus no snacking on glycemic outcomes
Bedtime snacking impairs nocturnal glycemia
Reduces time in range (TIR)
Does not decrease the frequency of hypoglycemia

Implication

Shows bedtime snacking impairs nocturnal glycemia in young children with Type 1 diabetes, implying more careful monitoring is needed.

Abstract

Bedtime snacking in young children with T1D impairs nocturnal glycemia and reduces TIR, without decreasing the frequency of hypoglycemia.

Discussion

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Cite This Study

Gökçe et al. (2025) studied this question.

synapsesocial.com/papers/6924e3e6c0ce034ddc34ebf4 https://doi.org/10.1038/s41387-025-00392-9

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Bedtime snacking and glycemic deterioration in young children with Type 1 diabetes on multiple daily injections: a randomized controlled crossover trialOriginal Research · 2025
2Bedtime Snack Composition and Overnight Glycemic Profiles in Children and Adolescents with Type 1 Diabetes Using Multiple Daily Injections: A Randomized Crossover StudyOriginal Research · 2026
3Evaluation of a Prediction-Based Bedtime Intervention in Reducing Nocturnal Low Glucose in Adults with Type 1 Diabetes: The DailyDose Bedtime Smart Snack Cross-over Study2025
4Nocturnal Glycemic Variability and Sleep Architecture in Children and Adolescents with Type 1 Diabetes: A Multi-Night Home Sleep StudyCohort Study · 2026
50883 Sleep and Circadian Health, Insulin Sensitivity, and Glycemic Control in Adolescents with Type 1 Diabetes2024 · 1 citations